Subway: Brown, Purple (rush hrs) to Merchandise Mart; Red to Grand(312) 661-1434 rickbayless.com41.890486 -87.630925 445 N Clark St (between Hubbard and Illinois Sts) River North, Chicago
Lunch (Tue–Fri), dinner (Tue–Sat) (closed Sun, Mon)Average main course: $37
Topolobampo ("Topolo" for short) is the most sophisticated and upscale of Rick Bayless's restaurants, and the one most frequented by President Obama and his family. (What, you thought they were eating tacos next door at Frontera?) As with all of Bayless's restaurants, the products used here are local and seasonal. So whether you're eating from the marisquera (sustainable seafood bar) or choosing one of the platillos fuertes (usually a protein—hen, lamb, lobster—dressed in a complex, chili-based sauce), you know you're eating the best the season has to offer. An ever-changing menu means it's hard to predict exactly what will be on offer day to day—but because Bayless is involved, it never really feels like a gamble.